Journal of Nephrology Advances

Journal of Nephrology Advances

Journal of Nephrology Advances – About

Open Access & Peer-Reviewed

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Journal of Nephrology Advances

Advancing molecular understanding of kidney pathophysiology through rigorous mechanistic research

Journal of Nephrology Advances (JNA) (ISSN 2574-4488) is a peer-reviewed, open access journal dedicated to publishing high-quality research that elucidates the molecular mechanisms underlying kidney disease. Our mission is to advance the scientific understanding of renal pathophysiology by disseminating cutting-edge discoveries in disease mechanisms, biomarker identification, and cellular pathway analysis.

JNA serves as a vital platform for researchers investigating how kidney diseases develop and progress at the molecular and cellular levels. We emphasize mechanistic insight, translational pathophysiology, and the molecular basis of renal dysfunction across diverse disease states.

Our Pathophysiology Focus

Journal of Nephrology Advances concentrates exclusively on the mechanisms of kidney disease rather than clinical management. We publish research that answers fundamental questions: How do molecular pathways contribute to glomerular injury? What cellular mechanisms drive tubular dysfunction? How do genetic variants alter renal physiology? What biomarkers reflect underlying pathological processes?

Research Priorities

JNA seeks manuscripts that provide mechanistic insight into renal pathophysiology, including molecular pathway analysis, disease model development, biomarker discovery, and cellular mechanism investigation. We value studies that bridge basic science with translational potential, offering deeper understanding of how kidney diseases work at fundamental levels.

Scope Areas

Glomerular Pathophysiology

Molecular mechanisms of podocyte injury, mesangial dysfunction, basement membrane alterations, and filtration barrier pathology

Tubular Mechanisms

Transport pathway disruption, epithelial cell injury, tubular regeneration processes, and segment-specific dysfunction

Acute Kidney Injury Pathogenesis

Ischemia-reperfusion mechanisms, oxidative stress pathways, inflammatory cascades, and cellular death signaling

Chronic Kidney Disease Progression

Fibrosis mechanisms, progressive nephron loss, metabolic dysregulation, and molecular drivers of disease advancement

Electrolyte Pathophysiology

Ion channel dysfunction, transporter defects, hormonal regulation mechanisms, and acid-base disturbance pathways

Hypertensive Nephropathy

Pressure-induced cellular injury, vascular remodeling mechanisms, and molecular links between hypertension and kidney damage

Diabetic Nephropathy Mechanisms

Hyperglycemia-induced cellular stress, advanced glycation pathways, metabolic reprogramming, and glucose toxicity mechanisms

Genetic Kidney Disorders

Monogenic disease mechanisms, variant pathogenicity, genotype-phenotype correlations, and molecular consequences of mutations

Biomarker Discovery

Novel molecular markers of disease processes, mechanistic biomarker validation, and pathway-specific indicators

Renal Immunology

Immune-mediated injury mechanisms, inflammatory pathway activation, autoimmune processes, and cellular immune responses

Experimental Models

Disease model development, pathway interrogation systems, in vitro mechanisms, and translational model validation

Molecular Nephrotoxicity

Drug-induced injury mechanisms, toxin pathways, cellular stress responses, and molecular bases of nephrotoxic effects

Why Publish with JNA

Mechanistic Focus

JNA provides a specialized forum for researchers investigating disease mechanisms, ensuring your work reaches an audience that values pathophysiological insight over clinical applications.

Rigorous Peer Review

Expert reviewers with deep expertise in renal pathophysiology evaluate manuscripts for mechanistic rigor, experimental validity, and translational relevance.

Open Access Impact

All articles are freely accessible worldwide, maximizing visibility and accelerating the dissemination of mechanistic discoveries to the global nephrology research community.

Rapid Publication

Efficient editorial processes ensure timely publication without compromising scientific quality, getting your mechanistic insights into the literature quickly.

Publication Types

Original Research
Mechanistic Studies
Pathway Analysis
Biomarker Reports
Disease Models
Review Articles
Molecular Methods
Data Reports
Brief Communications
Systematic Reviews

Peer Review Process

1

Initial Screening

Editorial team evaluates scope fit, ensuring submissions focus on mechanistic pathophysiology rather than clinical management.

2

Originality Check

Manuscripts undergo plagiarism screening to verify original contribution to the mechanistic understanding of kidney disease.

3

Expert Review

Specialists in renal pathophysiology assess experimental design, mechanistic interpretation, and translational significance.

4

Editorial Decision

Based on reviewer recommendations, the editorial board determines acceptance, revision needs, or rejection with constructive feedback.

Submission Guidelines

JNA welcomes submissions that advance mechanistic understanding of kidney pathophysiology. Manuscripts should emphasize molecular mechanisms, cellular pathways, disease models, or biomarker discovery.

  • Submit via our online portal or email to [email protected]
  • Follow detailed formatting requirements in our Instructions for Authors
  • Include mechanism-focused abstract highlighting pathophysiological insights
  • Provide detailed methods enabling experimental reproducibility
  • Discuss mechanistic implications and translational potential
  • Declare all funding sources and potential conflicts of interest
  • Ensure compliance with ethical standards for human/animal research

Editorial Leadership

JNA is guided by an expert editorial board comprising leading researchers in renal pathophysiology, molecular nephrology, and translational kidney science. Our editors are committed to maintaining rigorous standards while supporting authors in communicating mechanistic discoveries effectively.

Submit Your Mechanistic Research

Join the global community of researchers advancing pathophysiological understanding of kidney disease. Submit your mechanistic discoveries to Journal of Nephrology Advances today.

Contact Information: For inquiries about scope, submissions, or editorial policies, contact us at [email protected]